Charcot-Marie-Tooth Disease
CMTHereditary Motor and Sensory NeuropathyPeroneal Muscular Atrophy
📋Overview
Charcot-Marie-Tooth disease (CMT) is a group of inherited peripheral neuropathies characterized by progressive damage to the peripheral nerves. It is a legacy eponym referring to hereditary motor and sensory neuropathies (HMSN). Modern terminology classifies CMT into multiple genetic subtypes based on the underlying gene mutations and patterns of nerve involvement. The condition primarily affects the peripheral nerves responsible for muscle control and sensation in the limbs.
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