Familial Cutaneous Amyloidosis
📋Overview
This condition, also known as familial primary localized cutaneous amyloidosis, involves the accumulation of protein deposits specifically in the skin without affecting internal organs. It is distinguished from systemic forms of amyloidosis by its restriction to the dermal layers.
The disorder may manifest as lichen or macular amyloidosis and is typically associated with an underlying genetic predisposition. These skin changes result from the extracellular deposition of amyloid material, which is thought to arise from localized cellular processes.
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